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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRM2
All Species:
17.88
Human Site:
S511
Identified Species:
32.78
UniProt:
Q14416
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14416
NP_000830.2
872
95568
S511
C
L
Q
N
E
V
K
S
V
Q
P
G
E
V
C
Chimpanzee
Pan troglodytes
A3QNZ8
839
95029
N477
P
L
Q
R
Q
L
K
N
I
Q
D
I
S
W
H
Rhesus Macaque
Macaca mulatta
A3QP01
839
95041
K477
P
L
Q
R
Q
L
K
K
I
Q
D
I
S
W
H
Dog
Lupus familis
XP_541867
872
95696
S511
C
L
Q
N
E
V
K
S
V
Q
P
G
E
V
C
Cat
Felis silvestris
Mouse
Mus musculus
Q14BI2
872
95869
S511
C
L
Q
N
E
V
K
S
V
Q
P
G
E
V
C
Rat
Rattus norvegicus
P31421
872
95755
S511
C
L
Q
N
E
V
K
S
V
Q
P
G
E
V
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518731
870
95758
S511
C
R
K
N
E
M
K
S
V
Q
P
G
D
V
C
Chicken
Gallus gallus
XP_416842
879
98936
N520
C
A
P
N
E
M
K
N
M
Q
P
G
D
V
C
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5U9X3
867
97118
A507
P
G
Q
Y
K
K
T
A
E
G
Q
H
T
C
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91685
976
108467
Q572
E
V
G
M
I
K
K
Q
Q
G
D
T
C
C
W
Honey Bee
Apis mellifera
NP_001011624
933
103448
Q551
E
P
G
M
I
K
K
Q
Q
G
D
T
C
C
W
Nematode Worm
Caenorhab. elegans
Q09630
999
113258
C611
D
H
T
P
V
S
V
C
S
L
P
C
K
I
G
Sea Urchin
Strong. purpuratus
XP_784936
1474
165598
L1094
C
G
P
G
Q
V
K
L
I
Q
D
D
Q
I
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
27.6
27.6
98.1
N.A.
97.4
97.8
N.A.
88.3
67.9
N.A.
25.5
N.A.
45.7
47
39.9
32.2
Protein Similarity:
100
46.3
46.3
98.9
N.A.
98.5
98.7
N.A.
92.7
82.2
N.A.
43.8
N.A.
61.7
63.3
55.6
43.4
P-Site Identity:
100
26.6
26.6
100
N.A.
100
100
N.A.
73.3
60
N.A.
13.3
N.A.
6.6
6.6
6.6
33.3
P-Site Similarity:
100
53.3
46.6
100
N.A.
100
100
N.A.
93.3
86.6
N.A.
26.6
N.A.
13.3
6.6
20
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% A
% Cys:
54
0
0
0
0
0
0
8
0
0
0
8
16
24
62
% C
% Asp:
8
0
0
0
0
0
0
0
0
0
39
8
16
0
0
% D
% Glu:
16
0
0
0
47
0
0
0
8
0
0
0
31
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
16
16
8
0
0
0
0
0
24
0
47
0
0
8
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
16
% H
% Ile:
0
0
0
0
16
0
0
0
24
0
0
16
0
16
0
% I
% Lys:
0
0
8
0
8
24
85
8
0
0
0
0
8
0
0
% K
% Leu:
0
47
0
0
0
16
0
8
0
8
0
0
0
0
0
% L
% Met:
0
0
0
16
0
16
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
47
0
0
0
16
0
0
0
0
0
0
0
% N
% Pro:
24
8
16
8
0
0
0
0
0
0
54
0
0
0
0
% P
% Gln:
0
0
54
0
24
0
0
16
16
70
8
0
8
0
0
% Q
% Arg:
0
8
0
16
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
8
0
39
8
0
0
0
16
0
0
% S
% Thr:
0
0
8
0
0
0
8
0
0
0
0
16
8
0
0
% T
% Val:
0
8
0
0
8
39
8
0
39
0
0
0
0
47
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
16
16
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _